Do scientific discoveries happen more by accident or design?
* To identify the importance of the discovery of penicillin.
* To identify and evaluate the reasons for the discovery and manufacture
of penicillin as a drug widely available by the late 1940s.
Video Starter: Fleming and the discovery of Penicillin
Title: Fleming and the discovery of penicillin
Description: This short clip begins with an interview with Sir
Alexander Fleming. He recreates how he discovered that the staphylococcus
bacterium could not grow near the penicillium fungus which had contaminated
his petri dish. With thanks to Akzo Nobel.
Using the information from the links above and the chart below create
an interative poster
(a glog) illustrating how different factors combined to lead to the
discovery and development of penicilin.
The discovery of penicillin
What the advance was
Why it was important/ what the effect
He discovered a mould that he called penicillin.
It killed other bacteria.
It was anti-biotic. He could not grow this mould
in large quantities.
Florey and Chain
They made pure penicillin by freeze drying it.
This penicillin was given to mice that had been infected
with harmful bacteria. The mice survived. The uses of penicillin were
Florey and Chain
They performed the first human experiment using penicillin.
It was given to a patient suffering from a terrible infection.
The experiment was a success as the infection was
reduced but there was not enough of it to kill the infection completely.
The patient died.
US drug companies
These companies mass-produced penicillin.
Now infections and infectious diseases could be treated.
The fight against disease was won.
He found that antibiotics were in soils.
TB could be fought effectively. But soon it would
become resistant to this anti-biotic.
Note: this table has been taken from a worksheet that
a coleague passed to me. Unfortunately I do not know who originally
created this resource and am unable to cite the author. If you recognise
it, please let me know so that the appropriate acknowledgements can